renal-metabolic
Scannednpx machina-cli add skill rhavekost/clinical-toolkit/renal-metabolic --openclawRenal and Metabolic Calculators
Description
This skill provides structured calculation guidance for common renal and metabolic formulas used in clinical practice. It supports accurate input collection, calculation, interpretation, and safety caveats.
Quick Reference
| Tool | Use |
|---|---|
| CKD-EPI 2021 (Creatinine) | Estimate eGFR without race variable |
| CKD-EPI 2021 (Cystatin C) | eGFR using cystatin C or combined equation |
| Cockcroft-Gault (CrCl) | Drug dosing using creatinine clearance |
| Corrected Calcium | Adjust calcium for albumin |
| Corrected Sodium | Adjust sodium in hyperglycemia |
| Anion Gap | Metabolic acidosis assessment |
| Winters Formula | Expected pCO2 in metabolic acidosis |
| A-a Gradient | Oxygenation and V/Q evaluation |
| Friedewald LDL | Estimate LDL-C from standard lipids |
| BMI | Body mass index classification |
Interactive Mode (Lightweight)
- Confirm the clinical context and intended tool.
- Collect required inputs with units and timing.
- Validate inputs and resolve missing data.
- Calculate and present results with interpretation.
- Provide safety caveats and limitations.
Calculators
- CKD-EPI 2021 (Creatinine)
- CKD-EPI 2021 (Cystatin C)
- Cockcroft-Gault (CrCl)
- Corrected Calcium
- Corrected Sodium
- Anion Gap
- Winters Formula
- A-a Gradient
- Friedewald LDL
- BMI
Safety and Limitations
- Support tool only; not diagnostic or prescriptive.
- Use local policies and clinical judgment.
- Many formulas have population limits and invalid ranges.
References
Source
git clone https://github.com/rhavekost/clinical-toolkit/blob/main/dist/consumer/claude/renal-metabolic/SKILL.mdView on GitHub Overview
This skill provides structured calculation guidance for common renal and metabolic formulas used in clinical practice. It supports accurate input collection, calculation, interpretation, and safety caveats, covering eGFR (CKD-EPI 2021), Cockcroft-Gault, anion gap, Winters formula, A-a gradient, Friedewald LDL, corrected calcium and sodium, and BMI.
How This Skill Works
Using an interactive mode, the skill guides you to select a tool, collect required inputs with units and timing, validate data, and perform the calculation. It then presents results with interpretation and safety caveats, leveraging dedicated calculator modules (CKD-EPI 2021 creatinine, CKD-EPI 2021 cystatin C, Cockcroft-Gault, Anion Gap, Winters formula, A-a Gradient, Friedewald LDL, BMI, and related tools).
When to Use It
- Assess renal function for drug dosing using CKD-EPI 2021 (creatinine) or Cockcroft-Gault (CrCl).
- Evaluate acid-base status with Anion Gap and Winters formula for metabolic acidosis context.
- Estimate LDL-C from a standard lipid panel using Friedewald LDL.
- Correct electrolytes or biomarkers (Corrected Calcium, Corrected Sodium) in hyperglycemia or hypoalbuminemia.
- Classify BMI for nutritional assessment and dosing considerations.
Quick Start
- Step 1: Confirm the clinical context and select the required calculator.
- Step 2: Enter inputs with correct units and timing (e.g., creatinine, albumin, triglycerides).
- Step 3: Review the calculated result, interpretation, and safety caveats.
Best Practices
- Confirm the clinical context and choose the appropriate calculator.
- Validate inputs (units, timing, reference ranges) before calculating.
- Prefer CKD-EPI 2021 creatinine for eGFR; consider cystatin C or combined equations when available.
- Cross-check results with additional formulas if there are discrepancies.
- Document assumptions, limitations, and patient-specific factors in the interpretation.
Example Use Cases
- Calculate eGFR using CKD-EPI 2021 creatinine to guide nephrotoxic drug dosing.
- Determine creatinine clearance with Cockcroft-Gault for tailored antibiotic dosing.
- Assess metabolic acidosis risk using Anion Gap plus Winters formula for expected pCO2.
- Estimate LDL-C via Friedewald LDL from a standard lipid panel, noting triglyceride limits.
- Adjust calcium for albumin using Corrected Calcium and review sodium adjustments in hyperglycemia.
