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notebook-ai-agents-skill

npx machina-cli add skill fmschulz/omics-skills/notebook-ai-agents-skill --openclaw
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Notebook AI Agents Skill (Marimo First)

Build narrative-first, reproducible notebooks with strict run-all validation and clean data loading patterns. Prefer Marimo for new notebooks; support Jupyter only when needed for existing .ipynb files.

Instructions

  1. Prefer Marimo for new work. Create a .py notebook and keep cells small and deterministic.
  2. Outline the notebook (purpose, data sources, analysis steps, outputs) before coding.
  3. Use project-relative paths and DuckDB for data loading (TSV/Parquet preferred).
  4. Build plots with the shared style rules.
  5. Validate by running the notebook end-to-end (Marimo: marimo run; Jupyter: restart kernel + run all).

Quick Reference

TaskAction
Marimo docshttps://docs.marimo.io/
Jupyter (legacy)See docs/notebook_structure.md
Pixi + Jupyter (legacy)See docs/pixi_jupyter.md
Data loadingSee docs/data_loading_duckdb.md
Plot stylingSee docs/plot_style.md
ValidationSee docs/verification.md
Templates (legacy)templates/kiss_notebook_template.py

Input Requirements

  • Notebook scope and goals
  • Data file paths (TSV/Parquet preferred)
  • Python environment (Pixi recommended)
  • Marimo installed (preferred) or Jupyter available (legacy)

Output

  • Reproducible notebook with narrative markdown
  • Validated run-all execution
  • Plots and tables suitable for reporting

Quality Gates

  • Narrative text precedes code for each major step
  • All cells run top-to-bottom without hidden state
  • Data paths are project-relative and verified
  • Plots are labeled, readable, and consistent

Examples

Example 1: Run a Marimo notebook

marimo run notebooks/analysis.py

Example 2: Execute a Jupyter notebook (legacy)

python scripts/execute_notebook.py path/to/notebook.ipynb

Troubleshooting

Issue: Marimo fails to run due to missing dependencies Solution: Install required packages in the Pixi environment and re-run.

Issue: Jupyter notebook fails on restart Solution: Remove hidden state, re-run from a clean kernel, and fix warnings.

Source

git clone https://github.com/fmschulz/omics-skills/blob/main/skills/notebook-ai-agents-skill/SKILL.mdView on GitHub

Overview

This skill guides building reproducible, narrative-first analysis notebooks with Marimo as the preferred engine, while supporting Jupyter for legacy files. It emphasizes small, deterministic cells, project-relative data loading, and end-to-end run-all validation to ensure repeatable results and clear storytelling.

How This Skill Works

Create a .py notebook for Marimo-based workflows, outlining purpose, data sources, steps, and outputs before coding. Use project-relative paths and DuckDB for loading TSV/Parquet data, then build plots with a shared style. Validate by running the notebook end-to-end with marimo run (or Jupyter by restarting kernel and running all) to ensure reproducibility.

When to Use It

  • Starting a new data analysis notebook where reproducibility and narrative structure are paramount
  • Migrating an existing notebook to a Marimo-first workflow with strict run-all validation
  • Working with project-relative data paths and DuckDB-based loading for robust data access
  • Creating reporting-ready plots and tables with consistent styling
  • Validating end-to-end execution to ensure no hidden state affects results

Quick Start

  1. Step 1: Prefer Marimo for new work and create a .py notebook (small, deterministic cells)
  2. Step 2: Outline purpose, data sources, analysis steps, and outputs before coding
  3. Step 3: Use project-relative paths and DuckDB for data loading; run marimo run to validate

Best Practices

  • Outline notebook purpose, data sources, analysis steps, and outputs before coding
  • Prefer Marimo for new work; keep cells small and deterministic
  • Use project-relative paths and DuckDB for data loading (TSV/Parquet preferred)
  • Build plots with the shared style rules and label axes clearly
  • Validate by running the notebook end-to-end (Marimo: marimo run; Jupyter: restart kernel + run all)

Example Use Cases

  • Run a Marimo notebook: marimo run notebooks/analysis.py
  • Execute a Jupyter notebook (legacy): python scripts/execute_notebook.py path/to/notebook.ipynb
  • Refactor a notebook to use project-relative data paths and DuckDB for loading
  • Apply the shared plot styling to ensure consistency across reports
  • Perform end-to-end validation to confirm no hidden state affects outputs

Frequently Asked Questions

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