ginkgo-cloud-lab
Scannednpx machina-cli add skill K-Dense-AI/claude-scientific-skills/ginkgo-cloud-lab --openclawGinkgo Cloud Lab
Overview
Ginkgo Cloud Lab (https://cloud.ginkgo.bio) provides remote access to Ginkgo Bioworks' autonomous lab infrastructure. Protocols are executed on Reconfigurable Automation Carts (RACs) -- modular units with robotic arms, maglev sample transport, and industrial-grade software spanning 70+ instruments.
The platform also includes EstiMate, an AI agent that accepts human-language protocol descriptions and returns feasibility assessments and pricing for custom workflows beyond the listed protocols.
Available Protocols
1. Cell Free Protein Expression Validation
Rapid go/no-go expression screening using reconstituted E. coli CFPS. Submit a FASTA sequence (up to 1800 bp) and receive expression confirmation, baseline titer (mg/L), and initial purity with virtual gel images.
- Price: $39/sample | Turnaround: 5-10 days | Status: Certified
- Details: See references/cell-free-protein-expression-validation.md
2. Cell Free Protein Expression Optimization
DoE-based optimization across up to 24 conditions per protein (lysates, temperatures, chaperones, disulfide enhancers, cofactors). Designed for difficult-to-express and membrane proteins.
- Price: $199/sample | Turnaround: 6-11 days | Status: Certified
- Details: See references/cell-free-protein-expression-optimization.md
3. Fluorescent Pixel Art Generation
Transform a pixel art image (48x48 to 96x96 px, PNG/SVG) into fluorescent bacterial artwork using up to 11 E. coli strains via acoustic dispensing. Delivered as high-res UV photographs.
- Price: $25/plate | Turnaround: 5-7 days | Status: Beta
- Details: See references/fluorescent-pixel-art-generation.md
General Ordering Workflow
- Select a protocol at https://cloud.ginkgo.bio/protocols
- Configure parameters (number of samples/proteins, replicates, plates)
- Upload input files (FASTA for protein protocols, PNG/SVG for pixel art)
- Add any special requirements in the Additional Details field
- Submit and receive a feasibility report and price quote
For protocols not listed above, use the EstiMate chat to describe a custom protocol in plain language and receive compatibility assessment and pricing.
Authentication
Access Ginkgo Cloud Lab at https://cloud.ginkgo.bio. Account creation or institutional access may be required. Contact Ginkgo at cloud@ginkgo.bio for access questions.
Key Infrastructure
- RACs (Reconfigurable Automation Carts): Modular robotic units with high-precision arms and maglev transport
- Catalyst Software: Protocol orchestration, scheduling, parameterization, and real-time monitoring
- 70+ integrated instruments: Sample prep, liquid handling, analytical readouts, storage, incubation
- Nebula: Ginkgo's autonomous lab facility in Boston, MA
Source
git clone https://github.com/K-Dense-AI/claude-scientific-skills/blob/main/scientific-skills/ginkgo-cloud-lab/SKILL.mdView on GitHub Overview
Ginkgo Cloud Lab provides remote access to Ginkgo Bioworks' autonomous lab infrastructure, executing protocols on Reconfigurable Automation Carts with 70+ instruments. It supports cell-free protein expression experiments and fluorescent pixel-art generation, with EstiMate offering feasibility assessments and pricing for custom workflows. Users can select protocols, prepare inputs, and obtain pricing and ordering workflows directly in cloud.ginkgo.bio.
How This Skill Works
Users select a protocol on cloud.ginkgo.bio/protocols and run it on RACs via Catalyst Software, uploading inputs (FASTA for CFPS or PNG/SVG for pixel art). After submission, a feasibility report and price quote guide the ordering process. For custom workflows beyond the listed protocols, EstiMate can provide feasibility assessments and pricing.
When to Use It
- Run cell-free protein expression validation to confirm expression and baseline titer for a given FASTA sequence.
- Perform cell-free protein expression optimization using a DoE across up to 24 conditions per protein.
- Generate fluorescent pixel art from a PNG/SVG image using up to 11 E. coli strains.
- Interact with Ginkgo Cloud Lab services for protocol configuration, input preparation, or pricing.
- Request a custom workflow with EstiMate for feasibility assessment and pricing.
Quick Start
- Step 1: Go to https://cloud.ginkgo.bio/protocols and pick a protocol.
- Step 2: Configure parameters (samples/proteins, replicates, plates) and upload inputs (FASTA for CFPS, PNG/SVG for pixel art).
- Step 3: Add any special requirements in Additional Details and submit to receive feasibility and a price quote.
Best Practices
- Prepare CFPS FASTA sequences up to 1800 bp to ensure compatibility with protein expression protocols.
- If optimizing CFPS, design a DoE that covers up to 24 conditions per protein to maximize insight.
- Prepare PNG or SVG inputs for pixel art and ensure resolution falls within 48x48 to 96x96 pixels.
- Add all special requirements in the Additional Details field to avoid delays.
- Review the feasibility report and price quote before submitting to confirm scope and cost.
Example Use Cases
- Cell Free Protein Expression Validation: Submit a FASTA ≤1800 bp; price $39; turnaround 5-10 days.
- CFPS Optimization: DoE across up to 24 conditions; price $199; turnaround 6-11 days.
- Fluorescent Pixel Art Generation: 48x48 to 96x96 PNG/SVG; up to 11 strains; price $25; turnaround 5-7 days.
- Custom Protocol via EstiMate: Describe a non-listed workflow and receive feasibility and pricing.
- Order and manage a protocol: Configure inputs, additional details, and obtain a feasibility report and quote.
